Public Data Resource

LacI protein genotype-phenotype landscape data

Contact: David J. Ross..
Identifier: doi:10.18434/M32259
Version: 1.0


This data table contains the processed data for the LacI genotype-phenotype landscape, a quantitative measurement of the phenotype for approximately 60,000 variants of the E. coli LacI protein. The table includes, for example, the DNA barcode sequencing counts and the estimated fitness for each variant across 24 different chemical environments. It also includes the estimated dose-response curves for each variant under induction with IPTG.
Research Topics: Bioscience:Cell biology, Bioscience:Proteomics, Bioscience:Engineering/synthetic biology    
Subject Keywords: allostery, E. coli, Lac repressor, fitness landscape, genotype-phenotype relationships, DNA barcode sequencing, engineering biology    

Data Access

These data are public.

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About This Dataset

Version: 1.0
Cite this dataset
David J. Ross (2020), LacI protein genotype-phenotype landscape data, National Institute of Standards and Technology, (Accessed 2023-12-07)
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